GenScript Launches Industry's First Commercial CRISPR Genome Editing Service for Yeast

GenScript CRISPR service to deliver precise custom edited yeast strains in as few as 5 weeks

​​​​GenScript, the number one global provider of gene synthesis services, today announced the launch of its new CRISPR-based Yeast Genome Editing Service. The yeast service is the newest member of GenScript’s Microbial Genome Editing Service, which already includes a CRISPR-based bacterial genome editing service, powered by a novel λ Red-CRISPR/Cas9 technology. The company is the first to provide a CRISPR-based custom yeast cell line editing service commercially.

GenScript’s CRISPR-based Yeast Genome Editing Service can be used for knock-in, knock-out, or gene replacement in Saccharomyces cerevisiae. The service currently uses a two-vector system to target up to three genes simultaneously, while ensuring editing accuracy down to the base pair. Customers provide GenScript with their host yeast strain and the name or sequence of the gene to be edited. In as few as five weeks, GenScript delivers the newly engineered strain in glycerol stock with Sanger sequencing results. GenScript unveiled its Yeast Genome Editing Service at this February’s CRISPR Precision Gene Editing Congress in Boston, the second annual gathering of leaders in this rapidly-evolving field.

"GenScript developed CRISPR-based genome editing service for yeast to help researchers accelerate their research by easily leveraging this powerful, gene editing technology in one of the most widely used model organisms," said GenScript’s CRISPR Services Product Manager, Laura Geuss, Ph.D. "Our delivery of custom yeast strains edited with the precision afforded by CRISPR is poised to advance disease pathway studies, engineering of metabolic pathways, and production of biomolecules."

The genome-editing technology, CRISPR/Cas9 is being used by biologists in nearly every area of genetic research to delete, repair, or replace genes. The technology is considered faster, easier to use, and more precise than previous gene-editing techniques. In addition to the new Yeast Genome Editing Service, GenScript’s portfolio of CRISPR products and services include a gRNA design tool, gRNA constructs, genome-scale gRNA libraries, bacterial genome editing services and mammalian cell-line editing services.

For more information on GenScript’s CRISPR portfolio or to view case studies that demonstrate how the technology has been used, click here.

About GenScript - GenScript is the world leader in gene synthesis and a peptide, protein, and antibody research partner for fundamental life science research, translational biomedical research, early stage biopharmaceutical development, and synthetic biology. Since its founding in 2002, GenScript has provided services and products to scientists in more than 100 countries worldwide. The company delivers biological research services encompassing gene synthesis and molecular biology, peptide synthesis, custom antibodies, protein expression, antibody and protein engineering, in vitro and in vivo pharmacology and industrial synthetic biology products. For more information, visit


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